Adderall, a brand name for a drug that is a combination of amphetamine and dextroamphetamine, is a medication approved by the Food and Drug Administration to treat attention deficit hyperactivity disorder ADHD. It is also approved for the treatment of narcolepsy, which is a chronic sleep disorder characterized by sudden attacks of sleep and excessive daytime sleepiness. Adderall takes effect approximately after taking the drug.
Seven healthy male volunteers received a single oral dose of 5 mg, 10 mg, or 20 mg of d-amphetamine. Urine was collected at 2, 4, 8, 12, 18, and 24 h post-dose. Total urine volume was measured, and pH and creatinine were determined. Quantitation of urinary amphetamine in all specimens was performed by gas chromatography-mass spectrometry. There was considerable overlap of amphetamine concentrations in individual specimens following the various doses.
The time to peak concentration also varied widely at each dose, occurring in urines collected 2 to 18 h post-administration. The data demonstrated that amphetamine excretion increases with increasing urine flow and decreasing urine pH. Thus, a positive FUDT result for amphetamine means only that the individual was administered or self-administered amphetamine at some time prior to collection of the specimen.
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Adderall detection time – how long does adderall stay in your system?
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Full text links Cite Display options Display options. Abstract Seven healthy male volunteers received a single oral dose of 5 mg, 10 mg, or 20 mg of d-amphetamine. Similar articles Amphetamine excretion profile following multidose administration of mixed salt amphetamine preparation.
Cody JT, et al. J Anal Toxicol. GC-MS determination of amphetamine and methamphetamine in human urine for 12 hours following oral administration of dextro-methamphetamine: lack of evidence supporting the established forensic guidelines for methamphetamine confirmation. Valentine JL, et al.
What is this test?
Metabolic profile of amphetamine and methamphetamine following administration of the drug famprofazone. Greenhill B, et al. PMID: Amphetamine concentrations in human urine following single-dose administration of the calcium antagonist prenylamine-studies using fluorescence polarization immunoassay FPIA and GC-MS. Kraemer T, et al. Methamphetamine and amphetamine isomer concentrations in human urine following controlled Vicks VapoInhaler administration.
How long does adderall stay in your blood, urine and saliva?
Smith ML, et al. See all similar articles. Cited by 2 articles Evaluating the reliability of hair analysis in monitoring the compliance of ADHD patients under treatment with Lisdexamphetamine. Haedener M, et al. PLoS One. Kinetic and cardiovascular effects of acute topiramate dosing among non-treatment-seeking, methamphetamine-dependent individuals.
Johnson BA, et al.
Does this test have other names?
Prog Neuropsychopharmacol Biol Psychiatry. Epub Dec Clinical Trial. Publication types Research Support, U. Gov't, P. Adult Actions. Double-Blind Method Actions. Enzyme Multiplied Immunoassay Technique Actions. Gas Chromatography-Mass Spectrometry Actions. Guidelines as Topic Actions.
Humans Actions. Hydrogen-Ion Concentration Actions. Immunoassay Actions. Male Actions. Dextroamphetamine Actions. Silverchair Information Systems. Full text links [x] Silverchair Information Systems. Copy Download.